- Make
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- Nov 07, 2020
Top 10 David Andrew Sinclair Quotes
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- Last Updated on May 30, 2021
- People
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- Nov 07, 2020
Well, we can study aging in people, but of course those studies take decades. So what we try to do is we use simpler organisms to try and understand the basic mechanisms and so in my laboratory, for example, we use things like simple baker's yeast that we use to make bread.
- Car
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- Nov 07, 2020
We used to think that aging was a lot like, as if we were cars made fresh and youthful and then we've entered this breakdown in diet. What we didn't realize until recently is that we're much more complex than a car. We fix ourselves if we're broken.
- Long
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- Nov 07, 2020
So aging is really just the way we deteriorate over time. Lifespan on the other hand is how long we live. We typically refer to that as longevity.
- Live
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- Nov 07, 2020
The way to make a worm live longer is probably quite different from making a human live longer.
- Diseases
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- Nov 07, 2020
Well, originally we found resveratrol just in a test tube, looking for molecules that would turn on this enzyme, this protein that seems to defend against diseases in aging.
- Immune
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- Nov 07, 2020
The mice that had the resveratrol in their diet were still obese, but they were seemingly or relatively immune to the effects of the obesity. So their arteries were clear, their liver was nice and thin. Their bones were stronger. They could run further.
- People
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- Nov 07, 2020