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Last Updated on May 30, 2021

Day
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Nov 07, 2020

We went from a world where almost nobody knew anything about computers to a world where almost all of us are computer geeks for a huge fraction of our day. And I'd like to see that happen with the digital world of biological molecules, too.

Hope
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Nov 07, 2020

Most people are excited about themselves. Personal genome will deliver for inexpensively something about science to which you can relate. Just like computers are becoming something to which you can relate. It should be even easier to relate to your own biology, and I hope that will be one of the ways we get broader literacy in science.

Problems
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Nov 07, 2020

In my lab, we are constantly asking, 'What's the utility of this pure science that we're doing? Let's nudge it a little bit in a direction where people can connect to it and have some fun and/or help some very serious problems they have.'

Nov 07, 2020

When something like personal genomics or synthetic biology suddenly appears - it seems to suddenly appear - we might have been working on it for 30 years, but it seems to come out of nowhere. Then you need strategies for engaging a lot of people and thinking about where it will be going in the next few months or few years.

Nov 07, 2020

I think something very simple that everybody can do is they can participate in medical research as subjects. Personal genome project, for example, will take on as many subjects as we can find.

Health
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Nov 07, 2020

Terrorism is not a public health threat, relative to cancer and heart disease and malaria and so forth.

May
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Nov 07, 2020

It sounds a little bit too arrogant, but I think I certainly have a working model for how I conduct my life, and it may or may not be a correct worldview.

Nov 07, 2020

I think my original inspiration came from just natural curiosity about science and math and biology. In particular, I would say that, as I matured, it became more a feeling of trying to avoid the waste that occurs in the world where we have 6.5 billion minds. If you're a computer scientist, you can think of them as supercomputers.

Imagine
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Nov 07, 2020

We have a love affair with the idea of the 'natural,' even though we, as a species, are about as unnatural as you can imagine.

Nov 07, 2020

My laboratory and my obsession is about safety and building/engineering safety. It's not just a matter of saying we want the world to be safer; we have to create technology.

Day
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Nov 07, 2020

I will make the argument that we are poorly adapted to our current environment. I mean, we did not evolve to sit all day and be exposed to giant amounts of really tasty food.

Earth
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Nov 07, 2020

We will have to make a decision, as we go into new environments outside of earth, whether we want to drag along with us all our pathogens. We can, or we can't - it's up to us - but I consider that part of genome engineering is how we interact with the huge part of our genome which is our microbiome.

Price
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Nov 07, 2020

What I really wanted was for everybody to have their genome and, ideally, everybody to share their genome, and for that, we needed to bring the price way down.

New
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Nov 07, 2020

Making new petroleum should be as simple and straightforward as brewing beer.

High
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Nov 07, 2020

Reversal of ageing is high on my list of things to do, and not just because I'm getting old.

Never
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Nov 07, 2020

If we can come up with a way of backing up my brain into another that I have in my back-pack, we'll do it. People talk themselves out of things very easily. Things that they think are a million years away, or never, are actually four years away.

Copies
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Nov 07, 2020

The goal of reanimation research is not to make perfect living copies of extinct organisms, nor is it meant to be a one-off stunt in a laboratory or zoo. Reanimation is about leveraging the best of ancient and synthetic DNA.

Fat
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Nov 07, 2020

A few dozen changes to the genome of a modern elephant - to give it subcutaneous fat, woolly hair and sebaceous glands - might suffice to create a variation that is functionally similar to the mammoth. Returning this keystone species to the tundras could stave off some effects of warming.

Diversity
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Nov 07, 2020

Aside from bringing back extinct species, reanimation could help living ones by restoring lost genetic diversity. The Tasmanian devil (aka Sarcophilus harrisii) is so inbred at this point that most species members can exchange tumor cells without rejection.

Critically
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Nov 07, 2020

Preventing ongoing extinction of elephants, rhinoceroses, and other threatened species is critically important. By all means, we must set priorities for allocating finite conservation resources.

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