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Last Updated on May 30, 2021

February
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Nov 07, 2020

On February 19th, Dr. Collip found that he was unable to refine the extract by his method and was unable to keep up his supply to the wards. During the following six weeks, or longer, no extract was available for clinical tests. I believe the reason for this to be that Collip, wishing to keep his process a secret, had not kept careful records.

Graham
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Nov 07, 2020

It was an extremely trying time for me. Best was still intimate with MacLeod and the others about the laboratory. I was out of the picture entirely. MacLeod had taken over the whole physiological investigation. Collip had taken over the biochemistry. Professor Graham and Dr. Campbell had taken over the whole clinical aspect of the investigation.

Best
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Nov 07, 2020

Best said possibly the only thing that would have changed my attitude: 'What will happen to me?' 'Your friend MacLeod will look after you,' I said. Best replied, 'If you get out, I get out.' There was silence for some moments. I thought of all the joy of the early experiments which we had known together. Here was loyalty.

Medical
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Nov 07, 2020

Best and I worked in the sub-basement of the old medical building day and night. Time, meals, sleep - all were of secondary consideration. We had to get insulin into a form that was refined enough for continued clinical use.

Diabetes
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Nov 07, 2020

In the U.S., the incidence of diabetes has increased proportionately with the per capita consumption of sugar.

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